An approach to Repeat Breeder Syndrome. Cervical mucus immunoglobulin content does not alter sperm motility

Abstract

Repeat breeder (RB) syndrome plays a detrimental role on fertility and economic performance of dairy farms. Regarding its multifactorial origin, it has been stated that an immunological response in the female genital tract may impair sperm viability. Therefore, the aim of this study was to evaluate the concentration of immunoglobulins in cervical mucus of RB cows and its influence on sperm motility. Fifteen fertile cows and 32 RB cows were included in the study. Cervical mucus samples were collected at the time of artificial insemination (AI). The concentration of IgG and IgA was determined by radial immunodiffusion. Sperm motility in cervical mucus was evaluated by CASA system. Our results showed no significant differences between cows with or without RB syndrome regarding the concentration of immunoglobulins in cervical mucus and sperm motility. The only factor affecting sperm motility was time. Consequently, it may be probable that a local immune response against spermatozoa is not one common cause of RB syndrome.