RT Journal Article
T1 An approach to Repeat Breeder Syndrome. Cervical mucus immunoglobulin content does not alter sperm motility
A1 Villar, Sofía Lara
A1 Yáñez, Uxía
A1 Álvarez, Jacobo
A1 Alvariño, Mar
A1 Pérez-Marín, Carlos Carmelo
A1 Becerra González, Juan José
A1 García Herradón, Pedro José
A1 Peña Martínez, Ana Isabel
A1 Quintela Arias, Luis Ángel
K1 Repeat breeder cow
K1 Dairy cattle
K1 Cervical mucus
K1 Spermatozoa
K1 Immunity
AB Repeat breeder (RB) syndrome plays a detrimental role on fertility and economic performance of dairy farms. Regarding its multifactorial origin, it has been stated that an immunological response in the female genital tract may impair sperm viability. Therefore, the aim of this study was to evaluate the concentration of immunoglobulins in cervical mucus of RB cows and its influence on sperm motility. Fifteen fertile cows and 32 RB cows were included in the study. Cervical mucus samples were collected at the time of artificial insemination (AI). The concentration of IgG and IgA was determined by radial immunodiffusion. Sperm motility in cervical mucus was evaluated by CASA system. Our results showed no significant differences between cows with or without RB syndrome regarding the concentration of immunoglobulins in cervical mucus and sperm motility. The only factor affecting sperm motility was time. Consequently, it may be probable that a local immune response against spermatozoa is not one common cause of RB syndrome.
PB Scielo Brazil
SN 1806-9614
YR 2025
FD 2025-04-14
LK https://hdl.handle.net/10347/41042
UL https://hdl.handle.net/10347/41042
LA eng
NO Villar SL, Yáñez U, Álvarez J, Alvariño M, Pérez-Marín CC, Becerra JJ, Herradón PG, Peña AI, Quintela LA. An approach to repeat breeder syndrome. Cervical mucus immunoglobulin content does not alter sperm motility. Anim Reprod. 2025;22(2):e20240105. https://doi.org/10.1590/1984-3143-AR2024-0105
NO Uxía Yáñez was funded by Xunta de Galicia (Predoctoral Contract Ref. ED481A_2020/122).
DS Minerva
RD 30 abr 2026