A heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaging

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Física de Partículasgl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Inorgánicagl
dc.contributor.authorFondo Busto, María Matilde
dc.contributor.authorCorredoira Vázquez, Julio
dc.contributor.authorGarcía Deibe, Ana María
dc.contributor.authorSanmartín Matalobos, Jesús
dc.contributor.authorIglesias Rey, Ramón
dc.contributor.authorTaboada Antelo, Pablo
dc.date.accessioned2021-04-12T08:41:07Z
dc.date.available2021-04-12T08:41:07Z
dc.date.issued2016
dc.descriptionThe 20th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural Productsgl
dc.description.abstractA new ligand H3L, with internal compartments for allocating 3d metal ions and external donors to bind 4f ions, was synthesized and completely characterized. Reaction of H3L with zinc(II) and gadolin ium(III) salts allows isolating the heteronuclear complex {[ZnGd(HL)(NO3)(OAc)(CH3OH)](NO3)}∙6H2O (1·6H2O). The ability of 1·6H2O to act as a magnetic resonance imaging (MRI) contrast agent was evaluated and this study shows that both the transversal and longitudinal relaxivities are quite high but the T1/T2 ratio of 7.9 indicates that it could have even greater potential as a T2 contrast agentgl
dc.identifier.citationFondo, M., Corredoira-Vázquez, J., García-Deibe, A.M., Sanmartín-Matalobos, J., Iglesias, R. & Taboada, P. (2016). A heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaging. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin. (Ed.), Proceedings ECSOC-20: The 20Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2016. MDPI. doi: 10.3390/ecsoc-20-b003gl
dc.identifier.doi10.3390/ecsoc-20-b003
dc.identifier.isbn978-3-03842-192-4
dc.identifier.urihttp://hdl.handle.net/10347/25754
dc.language.isoenggl
dc.publisherMDPIgl
dc.relation.ispartofseriesElectronic Conference on Synthetic Organic Chemistry;20
dc.relation.publisherversionhttps://doi.org/10.3390/ecsoc-20-b003gl
dc.rights© 2016 by MDPI, Basel, Switzerland. Open Accessgl
dc.rights.accessRightsopen accessgl
dc.subjectGadoliniumgl
dc.subjectZincgl
dc.subjectMRI contrast agentgl
dc.subjectSchiff basegl
dc.subjectImidazolidinegl
dc.titleA heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaginggl
dc.typebook partgl
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscoveryab1b04cb-948d-47ef-8c5e-8b3aba62e728

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