Interest of 3-arylcoumarins as xanthine oxidase inhibitors

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánicagl
dc.contributor.authorMatos, Maria João Correia Pinto Carvalho de
dc.contributor.authorBorges, Fernanda
dc.contributor.authorSantana Penín, María Lourdes
dc.contributor.authorUriarte Villares, Eugenio
dc.contributor.authorMedda, Rosaria
dc.contributor.authorPintus, Francesca
dc.contributor.authorCaboni, Martina
dc.contributor.authorEra, Benedetta
dc.contributor.authorFais, Antonella
dc.contributor.authorPetrillo, Amalia di
dc.date.accessioned2021-04-13T11:35:33Z
dc.date.available2021-04-13T11:35:33Z
dc.date.issued2015
dc.descriptionThe 19th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural Products Chemistrygl
dc.description.abstractIn the current paper we studied the interest of a series of 3-arylcoumarin derivatives as xanthine oxidase inhibitors. For the best compound of the series, the 4’-methoxyphenyl-6-nitrocoumarin, it was determined the IC50 value and the type of inhibition. This work is a preliminary screening for further design and synthetize new non-purinergic derivatives as potential compounds involved in the inflammatory suppression, specially related to the goutgl
dc.identifier.citationMatos, M.J., Borges, F., Santanta, L., Uriarte, E., Medda, R., Pintus, F., Caboni, M., Era, B. Fais, A. & Di Petrillo, A. (2015). Interest of 3-arylcoumarins as xanthine oxidase inhibitors. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin, Proceedings ECSOC-19: The 19Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2015. MDPI. doi: 10.3390/ecsoc-19-b002gl
dc.identifier.doi10.3390/ecsoc-19-b002
dc.identifier.isbn978-3-03842-145-0
dc.identifier.urihttp://hdl.handle.net/10347/25880
dc.language.isoenggl
dc.publisherMDPIgl
dc.relation.ispartofseriesElectronic Conference on Synthetic Organic Chemistry;19
dc.relation.publisherversionhttps://doi.org/10.3390/ecsoc-19-b002gl
dc.rights© 2016 by MDPI, Basel, Switzerland. Open Accessgl
dc.rights.accessRightsopen accessgl
dc.subject3-Arylcoumarinsgl
dc.subjectCondensation reactiongl
dc.subjectCross-coupling reactiongl
dc.subjectXanthine oxidase inhibitorsgl
dc.subjectGoutgl
dc.titleInterest of 3-arylcoumarins as xanthine oxidase inhibitorsgl
dc.typebook partgl
dspace.entity.typePublication
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relation.isAuthorOfPublication0d623500-847d-42a3-a640-b799447f8750
relation.isAuthorOfPublication769c5d0c-04c9-43f2-89dc-e4eb770227d5
relation.isAuthorOfPublication.latestForDiscovery1ff49615-6fa1-4bcc-bd20-bbb9cf38a1a0

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