Asociación da diabetes mellitus e do tabaquismo co volume plaquetario medio na poboación xeral adulta: comparación co volume corpuscular medio dos hematíes
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Objetivo: Investigar los factores asociados con el volumen plaquetario medio (VPM) y determinar si existen diferencias en los factores asociados con el volumen corpuscular medio de los hematíes (VCM) en adultos.
Métodos: Se realizó un estudio transversal en 1504 individuos (44.5% varones; edad mediana de 52 años, rango de 18 a 91 años) seleccionados aleatoriamente de la población adulta general de un municipio en España. Se analizó la relación del VPM y del VCM con variables demográficas (edad y sexo), del estilo de vida (ejercicio físico, consumo de alcohol y tabaco) y metabólicas (índice de masa corporal y síndrome metabólico y sus componentes, incluyendo el diagnóstico de diabetes o prediabetes) a través de pruebas de laboratorio estandarizadas o cuestionarios validados.
Resultados: Después de ajustar por posibles factores de confusión, el tabaquismo se asoció positivamente tanto con el VPM como con el VCM. La diabetes y la prediabetes se asociaron positivamente con el VPM, pero no con el VCM. Factores adicionales asociados positivamente con el VCM (pero no con el VPM) fueron el consumo de alcohol, la edad y el sexo femenino. Factores adicionales asociados negativamente con el VCM (pero no con el VPM) fueron la actividad física moderada y un elevado índice de masa corporal.
Conclusiones: El VPM está aumentado en los fumadores y en personas con diabetes. Con excepción del tabaquismo, que también se asocia con un aumento del VCM, los factores asociados con el VPM y el VCM son diferentes en la población adulta.
Aim: This study aimed to investigate and compare factors associated with mean platelet volume (MPV) and mean red blood cell corpuscular volume (RBC-MCV) in the general adult population. Methods: We conducted a cross-sectional study on 1504 individuals (44.5% men; median age 52 years, range 18-91 years) randomly sampled from the general adult population. We measured MPV and RBC-MCV and determined their relationship with demographic (age and sex), lifestyle (physical exercise, alcohol and tobacco consumption), and metabolic (body mass index, metabolic syndrome, and diabetes or prediabetes diagnosis) variables. Results: After adjusting for potential confounders, smoking was positively associated with both MPV and RBC-MCV. Diabetes and prediabetes were positively associated with MPV, but not with RBC-MCV. Additional factors positively associated with RBC-MCV (but not with MPV) were alcohol consumption, age, and female sex. Additional factors negatively associated with RBC-MCV (but not with MPV) were moderate physical activity and high body mass index. Conclusions: MPV is increased in smokers and in patients with diabetes. With the exception of smoking, which is also associated with increased RBC-MCV, the factors associated with MPV and RBCMCV differ in the adult population.
Aim: This study aimed to investigate and compare factors associated with mean platelet volume (MPV) and mean red blood cell corpuscular volume (RBC-MCV) in the general adult population. Methods: We conducted a cross-sectional study on 1504 individuals (44.5% men; median age 52 years, range 18-91 years) randomly sampled from the general adult population. We measured MPV and RBC-MCV and determined their relationship with demographic (age and sex), lifestyle (physical exercise, alcohol and tobacco consumption), and metabolic (body mass index, metabolic syndrome, and diabetes or prediabetes diagnosis) variables. Results: After adjusting for potential confounders, smoking was positively associated with both MPV and RBC-MCV. Diabetes and prediabetes were positively associated with MPV, but not with RBC-MCV. Additional factors positively associated with RBC-MCV (but not with MPV) were alcohol consumption, age, and female sex. Additional factors negatively associated with RBC-MCV (but not with MPV) were moderate physical activity and high body mass index. Conclusions: MPV is increased in smokers and in patients with diabetes. With the exception of smoking, which is also associated with increased RBC-MCV, the factors associated with MPV and RBCMCV differ in the adult population.
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Traballo de Fin de Grao en Medicina. Curso 2024-2025.
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