Synthesis, characterization and self aggregation of a new neo-pentylamide cholic derivative (Na-n-penC)

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Abstract

The self-aggregation in aqueous solution of a new neo-pentyl amide of the 3-β-amino derivative of cholic acid (Na-n-penC) has been investigated in aqueous solution by surface tension and steady state-fluorescence spectroscopy of pyrene (used as a probe). The nature of the agregates was determined by transmission electron microscopy (TEM) revealing that vesicles are formed. The structure of the compound in the solid state was resolved by X-ray spectroscopy. The synthesis of the compound is also given

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The 10th International Electronic Conference on Synthetic Organic Chemistry session Supramolecular Chemistry

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Tellini, V.H.; Meijide, F.; Jover, A.; Galantini, L.; Novo, J.V.; Tato, J.V. Synthesis, characterization and self aggregation of a new neo-pentylamide cholic derivative (Na-n-penC), in Proceedings of the 10th International Electronic Conference on Synthetic Organic Chemistry, 1–30 November 2006, MDPI: Basel, Switzerland, doi:10.3390/ecsoc-10-01446

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© 2007 by MDPI, Basel, Switzerland. Open Access

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