The Reactions of Mitomycin C with Dithiols I. Reductive Activation
| dc.contributor.affiliation | Universidade de Santiago de Compostela. Departamento de Química Orgánica | gl |
| dc.contributor.author | Paz Castañal, Manuel María | |
| dc.date.accessioned | 2021-08-19T11:08:15Z | |
| dc.date.available | 2021-08-19T11:08:15Z | |
| dc.date.issued | 2010 | |
| dc.description | The 14th International Electronic Conference on Synthetic Organic Chemistry session Natural Products Chemistry | gl |
| dc.description.abstract | We report that the clinically used antitumor drug mitomycin C is reductively activated in vitro by simple thiols; a mechanism for this activation is proposed based on kinetic data and the identification of mitosene metabolites. The biological implications of these findings are discussed | gl |
| dc.identifier.citation | Proceedings of the 14th International Electronic Conference on Synthetic Organic Chemistry, 1–30 November 2010, MDPI: Basel, Switzerland, doi:10.3390/ecsoc-14-00482 | gl |
| dc.identifier.doi | 10.3390/ecsoc-14-00482 | |
| dc.identifier.isbn | 3-906980-24-3 | |
| dc.identifier.uri | http://hdl.handle.net/10347/26882 | |
| dc.language.iso | eng | gl |
| dc.publisher | MDPI | gl |
| dc.relation.ispartofseries | Electronic Conference on Synthetic Organic Chemistry;14 | |
| dc.relation.publisherversion | https://doi.org/10.3390/ecsoc-14-00482 | gl |
| dc.rights | © 2010 The author(s). Published by MDPI, Basel, Switzerland. Open Access | gl |
| dc.rights.accessRights | open access | gl |
| dc.title | The Reactions of Mitomycin C with Dithiols I. Reductive Activation | gl |
| dc.type | book part | gl |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 70589fec-3154-40e1-bcc7-1d1cc6e6f25a | |
| relation.isAuthorOfPublication.latestForDiscovery | 70589fec-3154-40e1-bcc7-1d1cc6e6f25a |
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