Agreement on Anterior Chamber Depth Measurement between Three Commercially Available Devices

Abstract

The present study aimed to assess the agreement of three commercially available devices on the measurement of anterior chamber depth (ACD) with and without compensation by central corneal thickness measurement (CCT). Fifty eyes were included in an observational cross-sectional study. Participants underwent a single visit during which devices were used to obtain the inclusion/exclusion (ARK510A, Canon TX-10) and studied (VX-120, Lenstar LS900 and EchoScan US-800) parameters. Based on invasiveness, tests were always performed in the same order by one researcher (to avoid inter-observer variability) and only in the right eye (to avoid overstating the precision of estimates) in each participant. The keratometry, autorefraction, intraocular pressure and anterior chamber angle values were used as inclusion criteria, while the CCT and ACD values were used in the agreement analysis between devices. There was a general and a paired difference in ACD measurements between devices (Greenhouse–Geisser: p ≤ 0.001; Sidak: all p ≤ 0.001). No significant difference was found in ACD measurements compensated by CCT values between the devices (Greenhouse–Geisser: p = 0.200). Pairwise analysis showed a significant difference in VX-120 vs. Lenstar (Sidak: p = 0.021). The differences in ACD measurements compensated by CCT values between the devices were clinically acceptable. Consequently, using these instruments interchangeably in daily routines based on this correction is justified.