Hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) determination of cocaine and its metabolites benzoylecgonine, ecgonine methyl ester, and cocaethylene in hair samples
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Abstract
This study reports the development and validation of a method using hydrophilic interaction liquid chromatography–tandem mass spectrometry (HILIC-MS/MS) for the analysis of cocaine and its metabolites benzoylecgonine (BE), ecgonine methyl ester (EME), and cocaethylene (CE) in hair samples.
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This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00216-009-3393-5
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Quintela, O., Lendoiro, E., Cruz, A., De Castro, A., Quevedo, A., Jurado, C., & López-Rivadulla, M. (2010). Hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) determination of cocaine and its metabolites benzoylecgonine, ecgonine methyl ester, and cocaethylene in hair samples. Analytical and Bioanalytical Chemistry, 396(5), 1703-1712. https://doi.org/10.1007/S00216-009-3393-5
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https://link.springer.com/article/10.1007/s00216-009-3393-5Sponsors
INCITE (Consellería de Innovación e Industria, Xunta de Galicia)
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Attribution-NonCommercial-NoDerivatives 4.0 International