The influence of diversity on the measurement of functional impairment : an international validation of the Amsterdam IADL Questionnaire in eight countries

Simple item page
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Psicoloxía Evolutiva e da Educacióngl
dc.contributor.authorDubbelman, Mark Anton
dc.contributor.authorVerrijp, Merike
dc.contributor.authorFacal Mayo, David
dc.contributor.authorSánchez Benavides, Gonzalo Andrés
dc.contributor.authorBrown, Laura J. E.
dc.contributor.authorFlier, Wiesje Maria van der
dc.contributor.authorJokinen, Hanna
dc.contributor.authorLee, Athene
dc.contributor.authorLeroi, Iracema
dc.contributor.authorLojo Seoane, Cristina
dc.contributor.authorMilošević, Vuk
dc.contributor.authorMolinuevo Guix, José Luís
dc.contributor.authorPereiro Rozas, Arturo X.
dc.contributor.authorRitchie, Craig William
dc.contributor.authorSalloway, Stephen
dc.contributor.authorStringer, Gemma
dc.contributor.authorZygouris, Stelios
dc.contributor.authorDubois, Bruno
dc.contributor.authorEpelbaum, Stéphane
dc.contributor.authorScheltens, Philip
dc.contributor.authorSikkes, Sietske A.M.
dc.date.accessioned2022-01-07T09:30:31Z
dc.date.available2022-01-07T09:30:31Z
dc.date.issued2020
dc.description.abstractIntroduction: To understand the potential influence of diversity on the measurement of functional impairment in dementia, we aimed to investigate possible bias caused by age, gender, education, and cultural differences. Methods: A total of 3571 individuals (67.1 ± 9.5 years old, 44.7% female) from The Netherlands, Spain, France, United States, United Kingdom, Greece, Serbia, and Finland were included. Functional impairment was measured using the Amsterdam Instrumental Activities of Daily Living (IADL) Questionnaire. Item bias was assessed using differential item functioning (DIF) analysis. Results: There were some differences in activity endorsement. A few items showed statistically significant DIF. However, there was no evidence of meaningful item bias: Effect sizes were low (ΔR2 range 0-0.03). Impact on total scores was minimal. Discussion: The results imply a limited bias for age, gender, education, and culture in the measurement of functional impairment. This study provides an important step in recognizing the potential influence of diversity on primary outcomes in dementia researchgl
dc.description.peerreviewedSIgl
dc.description.sponsorshipThe development of the Amsterdam IADL Questionnaire is supported by grants from Stichting VUmc Fonds and Innovatiefonds Zorgverzekeraars. The Amsterdam Alzheimer Center is supported by Stichting Alzheimer Nederland and Stichting VUmc Fonds. The present study is supported by a grant from Memorabel (733050205), which is the research program of the Dutch Deltaplan for Dementia. The chair of WMF is supported by the Pasman stichting. The clinical database structure for the Amsterdam Dementia Cohort was developed with funding from Stichting Dioraphte. DF, CLB and AXPR are supported by FEDER grant PSI2014-55316-C3-1-R, the Spanish National Research Agency grant PSI2017-89389-C2-1-R and the Galician Government GI-1807-USC: Ref. ED431-2017/27. GSB, JLM and the ALFA+ project has received funding from “la Caixa” Foundation (ID 100010434), under agreement LCF/PR/GN17/50300004 and the Alzheimer's Association and an international anonymous charity foundation through the TriBEKa Imaging Platform project (TriBEKa-17-519007). CWR and the work for EPAD has received support from the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement n° 115736. SE is supported by a joint collaborative grant by the AP-HP and Inria. LJEB, IL and GS were supported by the U.K. Engineering and Physical Sciences Research Council #EP/K015796/1. SZ is supported by the Robert Bosch Foundation Stuttgart within the Graduate Program People with Dementia in General Hospitals, located at the Network Aging Research (NAR), Heidelberg University, Germany. VM is supported by the Serbian Ministry of Education, Science and Technological Development, grant OI 173022. AL is partially supported by Institutional Development Award Number U54GM115677 from the National Institute of General Medical Sciences of the National Institutes of Health, which funds Advance Clinical and Translational Research (Advance-CTR)gl
dc.identifier.citationDubbelman, M. A., Verrijp, M., Facal, D., Sánchez-Benavides, G., Brown, L. J. E., Flier, W. M., Jokinen, H., Lee, A., Leroi, I., Lojo-Seoane, C., Milošević, V., Molinuevo, J. L., Pereiro Rozas, A. X., Ritchie, C., Salloway, S., Stringer, G., Zygouris, S., Dubois, B., Epelbaum, S., . . . Sikkes, S. A. M. (2020). The influence of diversity on the measurement of functional impairment: An international validation of the Amsterdam IADL Questionnaire in eight countries. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 12(1), e12021. https://doi.org/10.1002/dad2.12021gl
dc.identifier.doi10.1002/dad2.12021
dc.identifier.essn2352-8729
dc.identifier.urihttp://hdl.handle.net/10347/27327
dc.language.isoenggl
dc.publisherWiley Periodicals, Inc.gl
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/PSI2017-89389-C2-1-R/ES/ESTUDIO LONGITUDINAL DEL DETERIORO COGNITIVO EN EL ENVEJECIMIENTO NORMAL, DCL Y EA. EFECTOS DE UN PROGRAMA INTEGRADO DE ESTIMULACION COGNITIVA POR VIDEO-JUEGOS Y ESTIMULACIONgl
dc.relation.publisherversionhttps://doi.org/10.1002/dad2.12021gl
dc.rights© 2020 The Authors. Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, Inc. on behalf of Alzheimer’s Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are madegl
dc.rights.accessRightsopen accessgl
dc.subjectAlzheimer’s diseasegl
dc.subjectCross-cultural validationgl
dc.subjectDementiagl
dc.subjectDifferential item functioninggl
dc.subjectDiversitygl
dc.subjectFunctional declinegl
dc.subjectInstrumental activities of daily livinggl
dc.subjectItem response theorygl
dc.titleThe influence of diversity on the measurement of functional impairment : an international validation of the Amsterdam IADL Questionnaire in eight countriesgl
dc.typejournal articlegl
dc.type.hasVersionVoRgl
dspace.entity.typePublication
relation.isAuthorOfPublication3adcefeb-90f6-42c2-9e6b-5b8780b495b5
relation.isAuthorOfPublicationb5a86f68-c039-4181-8a92-ab45a0d01c73
relation.isAuthorOfPublication8d661513-25cb-4ef4-89f8-ff3a52976967
relation.isAuthorOfPublication.latestForDiscovery3adcefeb-90f6-42c2-9e6b-5b8780b495b5

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
2020_alzheimer_dementia_dubbelman_influence.pdf
Size:
739.26 KB
Format:
Adobe Portable Document Format
Description:
Download

Collections

NeuCogA-Aging
Psicoloxía Evolutiva e da Educación