Highly Enantioselective Cobalt‐Catalyzed (3+2) Cycloadditions of Alkynylidenecyclopropanes
Loading...
Identifiers
ISSN: 1433-7851
E-ISSN: 1521-3773
Publication date
Advisors
Tutors
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley
Metrics
Export
Abstract
Low‐valent cobalt complexes equipped with chiral ligands can efficiently promote highly enantioselective (3+2) cycloadditions of alkyne‐tethered alkylidenecyclopropanes. The annulation allows to assemble bicyclic systems containing five‐membered rings in good yields and with excellent enantiomeric ratios. We also present a mechanistic discussion based on experimental and computational data, which support the involvement of CoI/CoIII catalytic cycles
Description
This is the peer reviewed version of the following article: E. Da Concepción, I. Fernández, J. L. Mascareñas, F. López, Angew. Chem. Int. Ed. 2021, 60, 8182, which has been published in final form at https://doi.org/10.1002/anie.202015202. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
Bibliographic citation
E. Da Concepción, I. Fernández, J. L. Mascareñas, F. López, Angew. Chem. Int. Ed. 2021, 60, 8182.
Relation
Has part
Has version
Is based on
Is part of
Is referenced by
Is version of
Requires
Publisher version
https://doi.org/10.1002/anie.202015202Sponsors
This work received financial support from the Spanish MINECO (SAF2016‐76689‐R, CTQ2016‐78205‐P, CTQ2017‐84767‐P, PID2019‐106184GB‐I00 and PID2019‐108624RB‐I00), the Xunta de Galicia (ED431C 2017/19, 2015‐CP082, Centro Singular de Investigación de Galicia accreditation 2019–2022, ED431G 2019/03, and a predoctoral Fellowship to E. da C.) and the ERDF, ERC (Adv. Grant No. 340055)
Rights
© 2021 Wiley‐VCH GmbH. This article may be used for non-commercial purposes in accordance with Wiley-VCH Terms and Conditions for Self-Archiving