RT Journal Article
T1 Highly Enantioselective Cobalt‐Catalyzed (3+2) Cycloadditions of Alkynylidenecyclopropanes
A1 Concepción Vicente, Eduardo da
A1 Fernández, Israel
A1 Mascareñas Cid, José Luis
A1 López García, Fernando
K1 Alkylidenecyclopropane
K1 Cobalt
K1 Cycloaddition
K1 Earth-abundant metals
K1 Enantioselectivity
AB Low‐valent cobalt complexes equipped with chiral ligands can efficiently promote highly enantioselective (3+2) cycloadditions of alkyne‐tethered alkylidenecyclopropanes. The annulation allows to assemble bicyclic systems containing five‐membered rings in good yields and with excellent enantiomeric ratios. We also present a mechanistic discussion based on experimental and computational data, which support the involvement of CoI/CoIII catalytic cycles
PB Wiley
SN 1433-7851
YR 2021
FD 2021
LK http://hdl.handle.net/10347/26201
UL http://hdl.handle.net/10347/26201
LA eng
NO E. Da Concepción, I. Fernández, J. L. Mascareñas, F. López, Angew. Chem. Int. Ed. 2021, 60, 8182.
NO This is the peer reviewed version of the following article: E. Da Concepción, I. Fernández, J. L. Mascareñas, F. López, Angew. Chem. Int. Ed. 2021, 60, 8182, which has been published in final form at https://doi.org/10.1002/anie.202015202. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
NO This work received financial support from the Spanish MINECO (SAF2016‐76689‐R, CTQ2016‐78205‐P, CTQ2017‐84767‐P, PID2019‐106184GB‐I00 and PID2019‐108624RB‐I00), the Xunta de Galicia (ED431C 2017/19, 2015‐CP082, Centro Singular de Investigación de Galicia accreditation 2019–2022, ED431G 2019/03, and a predoctoral Fellowship to E. da C.) and the ERDF, ERC (Adv. Grant No. 340055)
DS Minerva
RD 28 abr 2026