Temporary Electrostatic Impairment of DNA Recognition: Light‐Driven DNA Binding of Peptide Dimers

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Molecularesgl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánicagl
dc.contributor.authorJiménez Balsa, Adrián
dc.contributor.authorPazos Chantrero, Elena
dc.contributor.authorMartínez Albardonedo, Borja
dc.contributor.authorMascareñas Cid, José Luis
dc.contributor.authorVázquez Sentís, Marco Eugenio
dc.date.accessioned2019-03-27T14:12:01Z
dc.date.available2019-03-27T14:12:01Z
dc.date.issued2012
dc.descriptionThis is the peer reviewed version of the following article: Jiménez‐Balsa, A. , Pazos, E. , Martínez‐Albardonedo, B. , Mascareñas, J. L. and Vázquez, M. E. (2012), Temporary Electrostatic Impairment of DNA Recognition: Light‐Driven DNA Binding of Peptide Dimers. Angew. Chem. Int. Ed., 51: 8825-8829, which has been published in final form at https://doi.org/10.1002/anie.201201627. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versionsgl
dc.description.abstractAppending negatively charged Glu8 tails to a peptide dimer derived from the GCN4 transcription factor leads to an effective suppression of its DNA binding. The specific DNA recognition can be restored by irradiation with UV light by using a photolabile linker between the acidic tail and the DNA binding peptidegl
dc.description.peerreviewedSIgl
dc.description.sponsorshipConsolider Ingenio. Grant Numbers: SAF2010‐20822‐C02, CTQ2009‐14431/BQU, CSD2007‐00006 Xunta de Galicia. Grant Numbers: INCITE09 209 084PR, PGIDIT08CSA‐047209PR, GRC2010/12 MINECOgl
dc.identifier.citationJiménez‐Balsa, A., Pazos, E., Martínez‐Albardonedo, B., Mascareñas, J. L. and Vázquez, M. E. (2012), Temporary Electrostatic Impairment of DNA Recognition: Light‐Driven DNA Binding of Peptide Dimers. Angew. Chem. Int. Ed., 51: 8825-8829. doi:10.1002/anie.201201627gl
dc.identifier.doi10.1002/anie.201201627
dc.identifier.essn1521-3773
dc.identifier.issn1433-7851
dc.identifier.urihttp://hdl.handle.net/10347/18482
dc.language.isoenggl
dc.publisherWileygl
dc.relation.publisherversionhttps://doi.org/10.1002/anie.201201627gl
dc.rights© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versionsgl
dc.rights.accessRightsopen accessgl
dc.subjectAmino acidsgl
dc.subjectDNA recognitiongl
dc.subjectPeptidesgl
dc.subjectPhotochemistrygl
dc.subjectProtein designgl
dc.titleTemporary Electrostatic Impairment of DNA Recognition: Light‐Driven DNA Binding of Peptide Dimersgl
dc.typejournal articlegl
dc.type.hasVersionAMgl
dspace.entity.typePublication
relation.isAuthorOfPublication205475ab-aa0b-4c1e-a0db-304fff413448
relation.isAuthorOfPublication5ae222c9-f626-432b-aac5-da78c06ed64f
relation.isAuthorOfPublication34f1e1e8-411b-4b42-a25c-253481d3abef
relation.isAuthorOfPublication.latestForDiscovery205475ab-aa0b-4c1e-a0db-304fff413448

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