Ruthenium bipyridyl complexes as photocleavable dimerizers: deactivation of DNA-binding peptides using visible light

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Molecularesgl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánicagl
dc.contributor.authorMosquera Mosquera, Jesús
dc.contributor.authorSánchez López, Mateo Isidro
dc.contributor.authorVázquez Sentís, Marco Eugenio
dc.contributor.authorMascareñas Cid, José Luis
dc.date.accessioned2014-12-05T13:36:28Z
dc.date.available2017-08-29T01:00:16Z
dc.date.issued2014-07-28
dc.description.abstractWe report a photolabile biselectrophilic Ru(II) complex that can be used for homo- or heterodimerization of cysteine-containing peptides. The resulting dimers can be efficiently disassembled by long-wavelength light. As proof-of-concept, we describe the preparation of homo- and heterodimeric bZIP peptides whose DNA-binding properties can be turned off using visible lightgl
dc.description.sponsorshipSpanish MINECO. Grant Numbers: SAF2010-20822-C02-01/02, CTQ2010-20714-C02-01/BQU, CSD2007-00006 ERDF Xunta de Galicia. Grant Numbers: GRC2010/12, GR2013-041, INCITE09 209084PR, EM2013/036 European Research Council. Grant Number: 340055 CAM. Grant Number: S2009/PPQ-1634, AVANCATgl
dc.identifier.citationMosquera, J., Sánchez, M. I., Vázquez, M. E. and Mascareñas, J. L. (2014), Ruthenium bipyridyl complexes as photocleavable dimerizers: deactivation of DNA-binding peptides using visible light. Chem. Commun., 50, 10975-10978 [doi: 10.1039/C4CC04512B]gl
dc.identifier.doi10.1039/c4cc04512b
dc.identifier.issn1364-548X
dc.identifier.urihttp://hdl.handle.net/10347/11968
dc.language.isoenggl
dc.publisherRoyal Society of Chemistrygl
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7/340055
dc.relation.publisherversionhttp://dx.doi.org/10.1039/C4CC04512Bgl
dc.rights.accessRightsopen accessgl
dc.titleRuthenium bipyridyl complexes as photocleavable dimerizers: deactivation of DNA-binding peptides using visible lightgl
dc.typejournal articlegl
dspace.entity.typePublication
relation.isAuthorOfPublication34f1e1e8-411b-4b42-a25c-253481d3abef
relation.isAuthorOfPublication5ae222c9-f626-432b-aac5-da78c06ed64f
relation.isAuthorOfPublication.latestForDiscovery34f1e1e8-411b-4b42-a25c-253481d3abef

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