Pizzi, AndreaOzores, Haxel LionelCalvelo Souto, MartínGarcía Fandiño, RebecaAmorín López, ManuelDemitri, NicolaTerraneo, GiancarloBracco, SilviaComottim AngiolinaSozzani, PieroMetrangolo, PierangeloGranja Guillán, Juan Ramón2024-12-302024-12-302019A. Pizzi, H. L. Ozores, M. Calvelo, R. García-Fandiño, M. Amorín, N. Demitri, G. Terraneo, S. Bracco, A. Comotti, P. Sozzani, C. X. Bezuidenhout, P. Metrangolo, J. R. Granja, Angew. Chem. Int. Ed. 2019, 58, 144721433-7851https://hdl.handle.net/10347/38302This is the peer reviewed version of the following article: A. Pizzi, H. L. Ozores, M. Calvelo, R. García-Fandiño, M. Amorín, N. Demitri, G. Terraneo, S. Bracco, A. Comotti, P. Sozzani, C. X. Bezuidenhout, P. Metrangolo, J. R. Granja, Angew. Chem. Int. Ed. 2019, 58, 14472, which has been published in final form at https://doi.org/10.1002/anie.201906599. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.A cyclic hexapeptide with three pyridyl moieties connected to its backbone forms a hydrogen-bonded dimer, which tightly encapsulates a single xenon atom, like a pearl in its shell. The dimer imprints its shape and symmetry to the captured xenon atom, as demonstrated by Xe-129 NMR spectroscopy, single-crystal X-ray diffraction, and computational studies. The dimers self-assemble hierarchically into tubular structures to form a porous supramolecular architecture, whose cavities are filled by small molecules and gases.engXenonHost-guestCyclic peptideSelf-assemblyGas confinement2306 Química orgánicajournal article10.1002/anie.201906599open access