Páramo Telle, ÓscarVence Deza, Xavier2026-04-292026-04-292026-04-15Páramo-Telle, Ó., & Vence, X. (2026). Industrial symbiosis in the wine value chain: a systematic review of research trends, barriers, and drivers. Journal of Industrial Ecology. https://doi.org/10.1007/s44498-026-00076-21088-1980https://hdl.handle.net/10347/47002The wine industry generates large volumes of by-products with high valorization potential, making Industrial Symbiosis (IS) a key strategy for its circular transition. However, the supporting academic literature remains fragmented, hindering a clear understanding of its dominant trends and knowledge gaps. This systematic review maps the research landscape of IS in the wine value chain to identify its trends, thematic focuses, and research clusters. Following the PRISMA methodology, a search was conducted in Scopus and Web of Science, yielding a final sample of 122 articles. The synthesis combined descriptive statistics with a thematic analysis of key dimensions (methodologies, geographical areas, by-products, recipient industries stakeholders, drivers and barriers), followed by a cluster analysis on the 99 original research articles to identify distinct thematic patterns and research approaches. Results reveal a research field in an early stage of maturity, with a predominance of experimental laboratory studies (60%) focused on grape pomace. Technological issues emerge as the primary barrier (91.9%), while environmental sustainability is the main driver (94.9%). Cluster analysis identifies three distinct research trends: a dominant technocentric stream focused on high-value applications, a second centered on bulk bioeconomy solutions, and a critically underdeveloped cluster focused on systemic implementation. This paper reveals a significant gap between the explored technical potential and the under-researched socio-organizational dimensions required for real-world implementation. In conclusion, this study establishes a roadmap for future research, highlighting the need to shift focus towards business models, collaborative governance, social acceptance, and scaling-up strategies to realize the full potential of IS.engThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons. org/licenses/by/4.0/.Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Wine value chainIndustrial symbiosisCircular economySystematic reviewCluster analysisIndustrial ecologyjournal article10.1007/S44498-026-00076-21530-9290open access