Varela Fernández, AlejandroVarela Carrete, Jesús ÁngelSaá Rodríguez, Carlos2020-10-052020-10-052012Varela-Fernández, A., Varela, J. A., Saá, C. (2012). Formation of Indoles, Dihydroisoquinolines and Dihydroquinolines by Ruthenium-Catalyzed Heterocyclizations. Synthesis, 44, 21, 3285-32950039-7881http://hdl.handle.net/10347/23341NOTICE: This is the peer reviewed version of the following article: Varela-Fernández, A., Varela, J. A., Saá, C. (2012). Formation of Indoles, Dihydroisoquinolines and Dihydroquinolines by Ruthenium-Catalyzed Heterocyclizations. Synthesis, 44, 21, 3285-3295. [doi: 10.1055/s-0032-1316539]. This article may be used for non-commercial purposes in accordance with Thieme Terms and Conditions for self-archivingIndoles, dihydroisoquinolines and dihydroquinolines were efficiently prepared by ruthenium-catalyzed heterocyclizations of aromatic homo- and bis-homopropargyl amines/amides in the presence of an amine/ammonium base-acid pair. These regioselective 5- and 6-endo cyclizations most probably occur by nucleophilic trapping of key Ru vinylidene intermediates.eng© Georg Thieme Verlag Stuttgart · New York. This article may be used for non-commercial purposes in accordance with Thieme Terms and Conditions for self-archivingHeterocyclizationsIndolesIsoquinolinesQuinolinesRutheniumVinylidenesjournal article10.1055/s-0032-13165391437-210Xopen access