Fondo Busto, María MatildeCorredoira Vázquez, JulioGarcía Deibe, Ana MaríaSanmartín Matalobos, JesúsIglesias Rey, RamónTaboada Antelo, Pablo2021-04-122021-04-122016Fondo, M., Corredoira-Vázquez, J., García-Deibe, A.M., Sanmartín-Matalobos, J., Iglesias, R. & Taboada, P. (2016). A heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaging. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin. (Ed.), Proceedings ECSOC-20: The 20Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2016. MDPI. doi: 10.3390/ecsoc-20-b003978-3-03842-192-4http://hdl.handle.net/10347/25754The 20th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural ProductsA new ligand H3L, with internal compartments for allocating 3d metal ions and external donors to bind 4f ions, was synthesized and completely characterized. Reaction of H3L with zinc(II) and gadolin ium(III) salts allows isolating the heteronuclear complex {[ZnGd(HL)(NO3)(OAc)(CH3OH)](NO3)}∙6H2O (1·6H2O). The ability of 1·6H2O to act as a magnetic resonance imaging (MRI) contrast agent was evaluated and this study shows that both the transversal and longitudinal relaxivities are quite high but the T1/T2 ratio of 7.9 indicates that it could have even greater potential as a T2 contrast agenteng© 2016 by MDPI, Basel, Switzerland. Open AccessGadoliniumZincMRI contrast agentSchiff baseImidazolidinebook part10.3390/ecsoc-20-b003open access