González Rodríguez, CarlosSuárez Álvarez, José RamónVarela Carrete, Jesús ÁngelSaá Rodríguez, Carlos2020-10-052020-10-052015González-Rodríguez, C., Suárez, J. R., Varela, J. A., Saá, C. (2015). Nucleophilic Addition of Amines to Ruthenium Carbenes: ortho‐(Alkynyloxy)benzylamine Cyclizations towards 1,3‐Benzoxazines. Angew. Chem. Int. Ed., 54, 9, 2724-27281433-7851http://hdl.handle.net/10347/23346NOTICE: This is the peer reviewed version of the following article: González-Rodríguez, C., Suárez, J. R., Varela, J. A., Saá, C. (2015). Nucleophilic Addition of Amines to Ruthenium Carbenes: ortho‐(Alkynyloxy)benzylamine Cyclizations towards 1,3‐Benzoxazines. Angew. Chem. Int. Ed., 54, 9, 2724-2728. [doi: 10.1002/anie.201410284]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archivingA new ruthenium-catalyzed cyclization of ortho-(alkynyloxy)benzylamines to dihydro-1,3-benzoxazines is reported. The cyclization is thought to take place via the vinyl ruthenium carbene intermediates that are easily formed from Cp*RuCl(cod) and N2CHSiMe3. The mild reaction conditions and the efficiency of the procedure allow the easy preparation of a broad range of new 2-vinyl-2-substituted 1,3-benzoxazine derivatives. Rearrangement of an internal Csp atom in the starting material into a tetrasubstituted Csp3 atom in the final 1,3-benzoxazine is highly remarkable.eng© 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archivingBenzoxazinesCarbenesCyclizationRearrangementsRutheniumjournal article10.1002/anie.2014102841521-3773open access