Matos, Maria João Correia Pinto Carvalho deBorges, FernandaSantana Penín, María LourdesUriarte Villares, EugenioMedda, RosariaPintus, FrancescaCaboni, MartinaEra, BenedettaFais, AntonellaPetrillo, Amalia di2021-04-132021-04-132015Matos, M.J., Borges, F., Santanta, L., Uriarte, E., Medda, R., Pintus, F., Caboni, M., Era, B. Fais, A. & Di Petrillo, A. (2015). Interest of 3-arylcoumarins as xanthine oxidase inhibitors. In J.A. Seijas, M.P. Vázquez Tato & S.K. Lin, Proceedings ECSOC-19: The 19Th International Electronic Conference On Synthetic Organic Chemistry: November 1-30, 2015. MDPI. doi: 10.3390/ecsoc-19-b002978-3-03842-145-0http://hdl.handle.net/10347/25880The 19th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic, Medicinal and Natural Products ChemistryIn the current paper we studied the interest of a series of 3-arylcoumarin derivatives as xanthine oxidase inhibitors. For the best compound of the series, the 4’-methoxyphenyl-6-nitrocoumarin, it was determined the IC50 value and the type of inhibition. This work is a preliminary screening for further design and synthetize new non-purinergic derivatives as potential compounds involved in the inflammatory suppression, specially related to the gouteng© 2016 by MDPI, Basel, Switzerland. Open Access3-ArylcoumarinsCondensation reactionCross-coupling reactionXanthine oxidase inhibitorsGoutbook part10.3390/ecsoc-19-b002open access