Faustino, HélioVarela Sandá, IvánMascareñas Cid, José LuisLópez García, Fernando2015-04-272015-04-272015-03-02Faustino, H., Varela, I., Mascareñas Cid, J.L. & López, F. (2015). Gold(I)-catalyzed [2 + 2 + 2] cycloaddition of allenamides, alkenes and aldehydes: a straightforward approach to tetrahydropyrans. "Chemical Science", 6, 2903-2908 [10.1039/C5SC00295H]2041-6520E-ISSN 2041-6539http://hdl.handle.net/10347/13247Allenamides participate as two-carbon components in an intermolecular [2 + 2 + 2] cycloaddition with alkenes and aldehydes when treated with catalytic amounts of a phosphite gold complex. The reaction is highly regio- and chemoselective, and works with different types of alkenes, including styrenes, enolethers or enamides, as well as with aromatic and aliphatic aldehydes. Accordingly, different types of 2,6- disubstituted tetrahydropyrans can be stereoselectively assembled in a single step from commercial or very accessible starting materialsengAllenamidesCycloadditionsAlkenesAldehydesTetrahydropyransMaterias::Investigación::23 Química::2302 Bioquímicajournal article10.1039/C5SC00295Hopen access