González, FélixMuiño Otero, RodrigoPereira Lestayo, VíctorCampos, RómuloBenedito Castellote, José Luis2020-05-192020-05-192011Díaz González, F.H., Muíño Otero, R., Pereira Lestayo, V., Campos Gaona, R. y Benedito Castellote, J.L. (2011). Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. J. Vet. Sci, vol. 12(3), 251-2551229-845Xhttp://hdl.handle.net/10347/22447Blood indicators are used as a tool to diagnose metabolic disorders. The present work was conducted to study the relationships among blood indicators of lipomobilization and hepatic function in high-yielding dairy cows. Two groups of Holstein cows were studied: 27 early lactation cows and 14 mid lactation cows from four different herds with similar husbandry characteristics in Galicia, Spain. Blood samples were obtained to measure beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), triglycerides (TG), and the activity of aspartate transaminase (AST) and gamma-glutamyl transferase. Cows in early lactation had higher levels of BHB and NEFA than mid lactation cows. High lipomobilization (NEFA ＞ 400 μmol/L) was detected in 67% and 7% of early lactation and mid lactation cows, respectively, while subclinical ketosis (BHB ＞ 1.2 mmol/L) was detected in 41% and 28% of the early lactation and lactation cows, respectively. TG concentrations were low in all cows suffering subclinical ketosis and in 61% of the cows with high lipomobilization. During early lactation, 30% of cows suffered hepatic lipidosis as detected by levels of AST. Compromised hepatic function was observed in early lactation cows as shown by lower concentrations of glucose, total protein, and ureaengCopyright © 2011 The Korean Society of Veterinary Science. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly citedhttps://creativecommons.org/licenses/by-nc/3.0/Blood biochemistryHepatic lipidosisHigh-yielding dairy cowKetosisjournal article10.4142/jvs.2011.12.3.2511976-555Xopen access