Rodríguez Vázquez, NuriaGarcía Fandiño, RebecaAmorín López, ManuelGranja Guillán, Juan Ramón2018-05-282018-05-282016-01-01Rodríguez-Vázquez, N., García-Fandiño, R., Amorín, M., & Granja, J. (2016). Self-assembling α,γ-cyclic peptides that generate cavities with tunable properties. Chemical Science, 7(1), 183-187. http://dx.doi.org/10.1039/c5sc03187ghttp://hdl.handle.net/10347/16735The design and synthesis of β-sheet-based self-assembling cyclic peptides with tunable cavities is described. The incorporation of a γ-amino acid with a hydroxyl group at C2 allows the incorporation of different groups that modify the internal properties of the resulting dimeric ensemble. These dimers can entrap different guests depending on the properties of the group at C2. The guest defines the geometry of the resulting aggregateeng(c) 2015 The Author(s). Published by Royal Society of Chemistry. This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedhttps://creativecommons.org/licenses/by/3.0/Self-assemblingCyclic peptidesSupramolecular chemistryMaterias::Investigación::23 Química::2306 Química orgánicajournal article10.1039/c5sc03187g2041-6539open access