Carreiro-DaCunha, EltonOrdóñez Mayán, LucíaBianchini, FlavianoMuñoz Barús, José Ignacio2026-04-202026-04-202026-05Carreiro DaCunha, E., Ordóñez Mayán, L., Bianchini, F., Muñoz Barúz, J.I. (2026). Possible adverse effects of mining activity on the neurocognitive development of children in the area of Cerro de Pasco (Perú). "Forensic Science International", vol. 3820379-0738https://hdl.handle.net/10347/46827Over the last 10 years there have been a number of studies examining the effects of exposure to environmental metal pollution on the population of the area of Cerro de Pasco (Peru). These have documented the prolonged pollution of the area caused by mining activity and recorded its pathological effects on the exposed population. The present work reports associations between the concentrations of metals in the hair of the area's children and their cognitive development, investigates the neurocognitive effects of exposure, and examines the change in environmental metal concentrations over time. Significant differences in hair metal concentrations were detected between exposed (case) and non-exposed (control) populations; in the former, the mean arsenic concentration was three times that of the latter, the cadmium concentration was double, and that of lead six times that of the latter. The mean total IQ of the exposed children was 12.3 points lower than those who were not exposed. Significant correlations were detected between the lead, cadmium, arsenic, manganese and antimony concentrations of the children's (combined exposed and non-exposed) hair and TIQ. In the exposed population, marked increases in hair metal concentrations were recorded between 2016 and 2018 (200 %), later falling by 2021 (though still exceeding the 2016 concentrations). Multivariate analyses involving big data are required to determine the covariables that influence the development of TIQ in exposed children, and to determine whether high toxic metal concentrations are an independent risk factor for cognitive deficit.eng© 2026 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND licenseAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Metal pollutionMining activityPathological effects3203 Medicina forensejournal article10.1016/j.forsciint.2026.1128611872-6283open access