Rodríguez Holguín, SocorroCorral Varela, María MontserratCadaveira Mahía, Fernando2020-07-282020-07-281999Rodríguez Holguín, S.; Corral, M.; Cadaveira, F.(1999).Event-related potentials elicited by a visual continuous performance task in children of alcoholics. Alcohol, 19, 23-30. doi: 10.1016/S0741-8329(99)00013-00741-8329http://hdl.handle.net/10347/23215Event-related potentials (ERPs) were recorded from a group of young children of alcoholics (HR; n -17, 7 females) with a high-density family-history of alcoholism and from a control group (CN; n -19, 10 females), ages 7–15 years old, during a visual continuous performance task. The P3 peak amplitude and the mean amplitude at five latency windows (300–800 ms) were measured at frontal (F3-Fz-F4), central (C3-Cz-C4) and parietal (P3-Pz-P4) electrodes. Data were analyzed using a mixed-model risk-group by stimulus-type (matching vs. nonmatching) by Electrode ANCOVA, with age as a covariate, for each of the scalp regions. The risk-group by stimulus- type interactions were significant at the parietal region for the P3 peak amplitude and for the 300–400 ms mean amplitude, although there were no risk-group main differences. The HR group manifested smaller differences between the amplitude of the matching and nonmatching condition than the CN group. These results suggest a deficient electrophysiological differentiation between relevant and irrelevant information and are discussed in relation to previous reports and to the characteristics of the sampleeng© 1999 Elsevier Science Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Event-related potentialsP3Visual continuous performance taskChildren of alcoholicsAlcoholismFamilial riskjournal article10.1016/S0741-8329(99)00013-01873-6823open access