Redondo Lago, Jaime MauroFernández Rey, JoséGonzález González, Daniel2024-09-032024-09-032019Redondo, J., Fernandez-Rey, J. & Gonzalez-Gonzalez, D. Is it possible to modify fear memories in humans with extinction training within a single day?. Psychological Research 83, 1340–1348 (2019)0340-0727http://hdl.handle.net/10347/34711This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00426-018-1017-4Extinction procedures have been used widely in the study of fear memories, and different positions have been adopted regarding the efficacy of such procedures and the mechanisms involved. It has been argued that extinction may interfere with the consolidation of the fear memory if the procedure is applied with the appropriate timing after acquisition. However, the opposite position is also held, that is, that the extinction does not achieve an elimination of the fear response. The aim of the present study is to test the short-term effects of immediate extinction in fear reduction when this extinction is preceded by a retrieval trial. For this, a procedure similar to that employed by Schiller et al. (Nature 463(7277): 49–53, 2010) was used, but in a single day and with white noise as an aversive unconditioned stimulus. The results indicate that a CS+ single retrieval trial before the extinction procedure after acquisition was more effective in fear reduction than standard immediate extinction.engFear memomyExtinctionSkin conductance response (SCR)journal article10.1007/s00426-018-1017-41430-2772open access