Mascareñas Cid, José LuisLópez García, FernandoGulías Costa, MoisésFernández Fernández, David2019-09-242021-09-092019http://hdl.handle.net/10347/19804Transition metal catalysis is an impressive tool to promote relevant synthetic transformations. A particularly appealing chase are metal C–H activation protocols which are at the vanguard of organic synthesis due to the advantages in terms of atomic waste prevention, one of the principles of the Green Chemistry,10 step economy and selectivity. On the other hand, annulations processes are among the most appealing transformations in terms of atom economy, efficiency and increase in molecular complexity. Merging these processes result in a powerful strategy in the synthesis of challenging bioactive molecules.1 During this PhD work we have discovered several cyclization and cycloaddition transition-metal promoted reactions that allow to access to relevant cyclic scaffolds.engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Catálise / CatalysisAnelacións / AnnulationsActivación C-H / C-H ActivationMetais de transición / Transition MetalsMaterias::Investigación::23 Química::2306 Química orgánica::230611 Compuestos organometálicosMaterias::Investigación::23 Química::2306 Química orgánica::230618 Estructuras de las moléculas orgánicasdoctoral thesisopen access