Vidal Pereira, XandroGulías Costa, MoisésMascareñas Cid, José LuisMAITI, DEBABRATA2022-08-022022-08-022022Vidal, X., Font, M., Gulías, M., & Mascareñas, J. L. (2022). Transition Metal‐Catalyzed desymmetrizations based on C-H activation processes. Weinheim, Germany: Wiley‐VCH GmbH. doi:10.1002/9783527834242.chf0138 Retrieved from https://onlinelibrary.wiley.com/doi/abs/10.1002/9783527834242.chf01389783527834242http://hdl.handle.net/10347/28979The relevance of chiral pharmaceuticals and fine chemicals has encouraged the development of synthetic methods that allow the preparation of these products in enantioselective form. Of the different strategies, those relying on the metal-catalyzed enantioselective activation of C-H bonds are especially appealing, owing to their step and atom economy. This is particularly the case in desymmetrization approaches, because of the simplicity of the reactants, and their intrinsic complexity increase characteristics. This article reviews the current state of the art on transition metal-catalyzed desymmetrizing functionalizations involving enantiodetermining C-H activation stepseng© 2022 Wiley-VCH GmbH. All rights reservedbook part10.1002/9783527834242restricted access