Freire Iribarne, Félix ManuelCobos Cabrera, Scarlet KatherineRodríguez Riego, RafaelQuiñoá Cabana, EmilioRiguera Vega, Ricardo2020-10-092021-09-142020Freire, F., Cobos, K., Rodríguez, R., Quiñoá, E. and Riguera, R. (2020), From Sergeants and Soldiers to Chiral Conflict Effects in Helical Polymers by Acting on the Conformational Composition of the Comonomers. Angew. Chem. Int. Ed.. Accepted Author Manuscript. doi:10.1002/anie.2020092151433-7851http://hdl.handle.net/10347/23376This is the peer reviewed version of the following article: Freire, F., Cobos, K., Rodríguez, R., Quiñoá, E. and Riguera, R. (2020), From Sergeants and Soldiers to Chiral Conflict Effects in Helical Polymers by Acting on the Conformational Composition of the Comonomers. Angew. Chem. Int. Ed.. Accepted Author Manuscript. doi:10.1002/anie.202009215, which has been published in final form at https://doi.org/10.1002/anie.202009215. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived VersionsDifferent communication mechanisms can be switched within a copolymer by acting on the conformational composition of the components and their chirality. Thus, a Sergeant and Soldiers effect is produced in two diastereomeric copolymer series —poly[( S )‐ 1 r ‐ co ‐( S )‐ 2 ( 1‐r ) ] and poly[( R )‐ 1 r ‐ co ‐( S )‐ 2 ( 1‐r ) ]— due to the presence in chloroform of a preferred conformation in ( S )‐ 2 , and a conformational equilibrium in 1 , where a P helix is induced independently of the absolute configuration of the Soldier. In THF, the presence of a conformational equilibrium at the pendants of the two components produces a reciprocal chiral enhancement effect by copolymerization of the two monomers, while in DMF, a third chiral to chiral communication switch is produced due to the presence of a single conformer at the pendant group of the two components. In such case, a Chiral Conflict or Chiral Accord effect is produced depending if the two components induce the same or the opposite helical senseeng© 2020 Wiley‐VCH GmbH. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archivingChiral CommunicationPoly(phenylacetylene)Sergeants and SoldiersChiral CoalitionChiral Conflictjournal article10.1002/anie.2020092151521-3773open access