Vilela-Picos, MarcosNovelli, FedericaPazó, AntíaMéndez-Ardoy, AlejandroMarafon, GiuliaAmorín López, ManuelMoretto, AlessandroGranja Guillán, Juan Ramón2025-01-242025-01-242023-11-092451-9308https://hdl.handle.net/10347/39030Cyclic peptides containing a β-unsaturated amino acid are programmed to switch between monomeric form and self-assembled peptide nanotube structures upon light irradiation. The process is triggered by the reversible E-Z isomerization of the unsaturated β-amino acid that forces the peptide to swap from the folded (unassembled) to the flat conformation (assembled). The process is also tuned by the pH media, which provides a double checkpoint control in the molecular assembly of the peptide nanotubes. The light-driven assembly process can be triggered in a confined environment, and the resulting nanotubes allow the inter-vesicle communication, providing droplets with self-fusiogenic properties.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Nanotubos de péptidosFotoensambladoresIsomerización luz-inducidaPolímeros supramolecularesMicrofluidos2306 Química orgánicajournal article10.1016/j.chempr.2023.10.005open access