Alfonso Rancaño, María AmparoRodríguez Vieytes, MercedesBotana López, Luis Miguel2017-10-202017-10-202016-01-28Alfonso, A.; Vieytes, M.R.; Botana, L.M. Yessotoxin, a Promising Therapeutic Tool. Mar. Drugs 2016, 14, 30http://hdl.handle.net/10347/15901Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implicationseng© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)http://creativecommons.org/licenses/by/4.0/Yessotoxin (YTX)ApoptosisAutophagyCellular deathSignal transductionCytoskeletonImmune systemAlzheimerGlucose metabolismYessotoxin, a promising therapeutic tooljournal article10.3390/md140200301660-3397open access