Leira Feijóo, YagoBatalla Vázquez, PilarMorgado, MarianaMachado, VanessaMendes, José JoãoBotelho, JoãoBlanco Carrión, Juan2025-09-162025-09-162025-05-06Leira Y, Batalla P, Morgado M, Machado V, Mendes JJ, Botelho J, Blanco J. The Use of Video-Based Learning to Elucidate the Biological Mechanisms Linking Oral Health With Specific Systemic Medical Conditions. Spec Care Dentist. 2025 May-Jun;45(3):e70057. doi: 10.1111/scd.70057. PMID: 40400096; PMCID: PMC12095897.0275-1879https://hdl.handle.net/10347/42827Introduction: Video-based learning has emerged as a powerful tool to overcome the well-documented limitations of traditional lectures. Hence, the aim of this study was to investigate the impact of the implementation of a video animation on academic performance and student's opinion. Methods: A video animation on biological mechanisms behind the link between periodontitis and its treatment with atherosclerosis and diabetes was projected in addition to the traditional lecture to 46 4th-year undergraduate dental students enrolled in the 2024-2025 academic course at the University of Santiago de Compostela. A multiple-choice test including eight questions was delivered to assess student's knowledge after the lesson. Also, student´s perception on the use of this video animation was evaluated by the User Experience Questionnaire. Results: The video animation tested in this study shows excellent results in terms of attractiveness, perspicuity, efficiency and dependability. Good results are observed for stimulation and novelty. Almost 3/4 of undergraduate dental students obtained very good or outstanding marks in the test. Conclusions: The use of a video animation to explain biological mechanisms underlying the link between periodontitis and systemic diseases appears to be a helpful tool for undergraduate dental students.eng© 2025 The Author(s). Special Care in Dentistry published by Special Care Dentistry Association and Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are madeAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/AtherosclerosisDental educationDiabetesOral healthPeriodontologyVideo‐based learningjournal article10.1111/scd.70057open access