Sánchez López, Mateo IsidroMosquera Mosquera, JesúsVázquez Sentís, Marco EugenioMascareñas Cid, José Luis2014-12-052017-08-292014-07-15Sánchez, M. I., Mosquera, J., Vázquez, M. E. and Mascareñas, J. L. (2014), Reversible Supramolecular Assembly at Specific DNA Sites: Nickel-Promoted Bivalent DNA Binding with Designed Peptide and Bipyridyl–Bis(benzamidine) Components. Angew. Chem. Int. Ed., 53: 9917–9921. doi: 10.1002/anie.2014057261521-3773http://hdl.handle.net/10347/11965At specific DNA sites, nickel(II) salts promote the assembly of designed components, namely a bis(histidine)-modified peptide that is derived from a bZIP transcription factor and a bis(benzamidine) unit that is equipped with a bipyridine. This programmed supramolecular system with emergent properties reproduces some key characteristics of naturally occurring DNA-binding proteins, such as bivalence, selectivity, responsiveness to external agents, and reversibility.eng© WILEY-VCH Verlag GmbH & Co. KGaA, WeinheimDNA recognitionMinor-groove bindersPeptidesSelf-assemblySupramolecular chemistryMaterias::Investigación::23 Química::2302 Bioquímicajournal article10.1002/anie.201405726open access