Granja Guillán, Juan RamónAmorín López, ManuelVilela Picos, Marcos2025-04-232025-04-232025https://hdl.handle.net/10347/40962The dynamic behaviour of supramolecular systems has facilitated the incorporation of stimuli-responsive capabilities into these materials, thereby broadening their range of applications. In this context, self-assembling cyclic peptide nanotubes emerge as a promising alternative for the construction of this type of systems. These tubular assemblies are formed by the controlled stacking of cyclic peptide units with a flat conformation through hydrogen bonding interactions. This doctoral thesis proposes different strategies for obtaining stimuli-responsive cyclic peptide nanotubes in order to control their self-assembly process or to develop drug delivery applications. The results represent an initial step towards future new self-assembly properties and biological applications for cyclic peptide nanotubes.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/cyclic peptidesnanotubesself-assemblystimuli-responsivedrug delivery230224 Péptidosdoctoral thesisopen access