Mariño Lorenzo, PaulaGonzález Izquierdo, AndreaRodríguez Carnero, María GemmaFernández Pombo, AntíaIglesias Fernández, AlbaCouselo Carreira, MarcosTejera Pérez, CristinaBellido Guerrero, DiegoMartínez Olmos, Miguel ÁngelLeis Trabazo, María RosauraCasanueva Freijo, FelipeCrujeiras Martínez, Ana Belén2023-01-032023-01-032022Paula M. Lorenzo, Andrea G. Izquierdo, Gemma Rodriguez-Carnero, Antía Fernández-Pombo, Alba Iglesias, Marcos C Carreira, Cristina Tejera, Diego Bellido, Miguel A Martinez-Olmos, Rosaura Leis, Felipe F Casanueva, Ana B Crujeiras, Epigenetic Effects of Healthy Foods and Lifestyle Habits from the Southern European Atlantic Diet Pattern: A Narrative Review, Advances in Nutrition, Volume 13, Issue 5, September 2022, Pages 1725–1747, https://doi.org/10.1093/advances/nmac0382161-8313http://hdl.handle.net/10347/29719Recent scientific evidence has shown the importance of diet and lifestyle habits for the proper functioning of the human body. A balanced and healthy diet, physical activity, and psychological well-being have a direct beneficial effect on health and can have a crucial role in the development and prognosis of certain diseases. The Southern European Atlantic diet, also named the Atlantic diet, is a unique dietary pattern that occurs in regions that present higher life expectancy, suggesting that this specific dietary pattern is associated with positive health effects. In fact, it is enriched with nutrients of high biological value, which, together with its cooking methods, physical activity promotion, reduction in carbon footprint, and promoting of family meals, promote these positive effects on health. The latest scientific advances in the field of nutri-epigenetics have revealed that epigenetic markers associated with food or nutrients and environmental factors modulate gene expression and, therefore, are involved with both health and disease. Thus, in this review, we evaluated the main aspects that define the Southern European Atlantic diet and the potential epigenetic changes associated with them based on recent studies regarding the main components of these dietary patterns. In conclusion, based on the information existing in the literature, we postulate that the Southern European Atlantic diet could promote healthy aging by means of epigenetic mechanisms. This review highlights the necessity of performing longitudinal studies to demonstrate this proposaleng© The Author(s) 2022. Published by Oxford University Press on behalf of the American Society for Nutrition. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.comAtribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/Atlantic dietBiomarkersBioactive compoundsEpigeneticsHealthy foodsLifestyleNutri-epigeneticsPreventionPrecision nutritionjournal article10.1093/advances/nmac0382156-5376open access