Blanco Álvarez, JorgeFlament Simon, Saskia Camille2021-04-232021-04-232021http://hdl.handle.net/10347/26039Escherichia coli is the leading cause of urinary tract and bloodstream infections in humans and animals. The treatment of these infections has been seriously complicated by the appearance of multidrug-resistant isolates and especially by the rapid dissemination of extended-spectrum betalactamase- producing E. coli (ESBLEC). The present doctoral thesis includes six studies in which we evaluated the prevalence, the phenotypic and the genotypic characteristics of sequence type 131 (ST131) strains and other high-risk clones among E. coli strains isolated from patients with extraintestinal infections. We also study animals (pigs and dogs) as reservoirs for ST131 strains and other high-risk clones.engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Escherichia coliclonal structurevirulence genesantibiotic resistancehigh-risk clonesplasmidomeMaterias::Investigación::32 Ciencias médicas::3201 Ciencias clínicas::320103 Microbiología clínicaMaterias::Investigación::24 Ciencias de la vida::2415 Biología molecular::241501 Biología molecular de microorganismosMaterias::Investigación::31 Ciencias agrarias::3109 Ciencias veterinarias::310905 Microbiologíadoctoral thesisopen access