Martínez Insua, ArturoGuitián Rivera, FranciscoLópez Píriz, RobertoBartolomé, José F.Cabal, BelénEsteban Tejeda, LeticiaTorrecillas, RamónMoya, José S.2020-05-202020-05-202014Martinez A, Guitián F, López-Píriz R, Bartolomé JF, Cabal B, Esteban-Tejeda L, et al. (2014) Bone Loss at Implant with Titanium Abutments Coated by Soda Lime Glass Containing Silver Nanoparticles: A Histological Study in the Dog. PLoS ONE 9(1): e86926. https://doi.org/10.1371/journal.pone.0086926http://hdl.handle.net/10347/22459The aim of the present study was to evaluate bone loss at implants connected to abutments coated with a soda-lime glass containing silver nanoparticles, subjected to experimental peri-implantitis. Also the aging and erosion of the coating in mouth was studied. Five beagle dogs were used in the experiments. Three implants were placed in each mandible quadrant: in 2 of them, Glass/n-Ag coated abutments were connected to implant platform, 1 was covered with a Ti-mechanized abutment. Experimental peri-implantitis was induced in all implants after the submarginal placement of cotton ligatures, and three months after animals were euthanatized. Thickness and morphology of coating was studied in abutment cross-sections by SEM. Histology and histo-morphometric studies were carried on in undecalfied ground slides. After the induced peri-implantitis: 1.The abutment coating shown losing of thickness and cracking. 2. The histometry showed a significant less bone loss in the implants with glass/n-Ag coated abutments. A more symmetric cone of bone resorption was observed in the coated group. There were no significant differences in the peri-implantitis histological characteristics between both groups of implants. Within the limits of this in-vivo study, it could be affirmed that abutments coated with biocide soda-lime-glass-silver nanoparticles can reduce bone loss in experimental peri-implantitis. This achievement makes this coating a suggestive material to control peri-implantitis development and progression.eng© 2014 Martinez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are creditedhttps://creativecommons.org/licenses/by/4.0/CoatingsSilverNanoparticlesEphiteliumHistologyInflammationDogsSurface treatmentsjournal article10.1371/journal.pone.00869261932-6203open access