Figueiredo, Marilia AndradeAndrade, Natalia SilvaBlanco Carrión, AndrésMedina, Janaina BragaGallottini, MarinaOrtega, Karem L.2024-03-142024-03-142023Figueiredo, M. A., Andrade, N. S., Blanco Carrión, A., Medina, J. B., Gallottini, M., & Ortega, K. L. (2023). Bleeding during tooth extraction in patients with chronic kidney disease: A cross-sectional pilot study. Oral Diseases, 00, 1–8. https://doi.org/10.1111/odi.147091354-523Xhttp://hdl.handle.net/10347/33194Objective: This work measures the intra-operative bleeding in end-stage renal disease patients and assesses whether laboratory coagulation tests and nitrogenous compounds are related to a higher bleeding risk. Methods:Laboratory tests were performed on the day of surgery and some patients with thrombocytopenia and values above the normal levels of international normalised ratio (INR), thrombin time (TT) and activated partial thromboplastin time (aPTT) were identified. Results: Haemostatic time ranged from 2 to 35 min (mean of 8.51 min) after suture. Bleeding volume ranged from 0.02 to 67.06 mL (mean of 4.38 mL) and the bleeding volume per minute ranged from 0.05 to 2.10 mL/min (median of 0.6 mL/min). Only seven patients (16.27%) had abnormal bleeding (more than 0.6 mL/min). Spearman's coefficient showed weak correlations between bleeding volume (mL/min) and serum urea (r = 0.226), TT (r = 0.227), plasma urea (r = 0.148) and creatinine (r = 146), as well as very weak correlations with all other variables (r < 0.140) such as age, haemodialysis time, glycaemia, glycated haemoglobin, platelets, INR, aPTT and fibrinogen. Conclusion: It was not possible to associate any laboratory test or nitrogenous compounds present in the blood and saliva with an increased bleedingeng© 2023 The Authors. Oral Diseases published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly citedAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/BleedingChronic kidney diseaseEnd-stage renal diseaseHaemodialysisNitrogenous compoundsOral surgeryTooth extractionjournal article10.1111/odi.147091601-0825open access