Granja Guillán, Juan RamónMontenegro García, JavierFernández Caro, Héctor2021-02-182021-12-182020http://hdl.handle.net/10347/24499In this Ph.D. dissertation, we have applied supramolecular strategies to promote intracellular delivery of diverse molecules and design potential thermoresponsive systems. Host-guest chemistry has been exploited to encapsulate and deliver different anionic probes such as pyranine, as well as anionic peptides with low self-delivery efficiency. Finally, we have designed potential thermoresponsive supramolecular materials based on self-assembling cyclic peptide nanotubes (SCPNs).engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Supramolecular chemistryMolecular recognitionCyclodextrinsGold nanoparticlesCellpenetrating peptidesCytosolic deliveryMaterias::Investigación::23 Química::2302 Bioquímica::230224 PéptidosSupramolecular strategies for intracellular delivery and design of new thermoresponsive materialsdoctoral thesisopen access