Pérez Mayán, LeticiaRamil Criado, MaríaCela Torrijos, RafaelRodríguez Pereiro, Isaac2021-09-232021-09-232021Journal of Food Composition and Analysis 104 (2021) 104184. https://doi.org/10.1016/j.jfca.2021.1041840889-1575http://hdl.handle.net/10347/26945Liquid chromatography tandem mass spectrometry (LC–MS/MS) has been combined with different sample preparation strategies to determine potential pesticide residues existing in wine. Herein, we propose the on-line coupling between solid-phase extraction (SPE), based on a reversed-phase polystyrene-divinyl benzene (PS-DVB) sorbent, and LC–MS/MS for the automated monitoring of a selection of 48 pesticides (37 fungicides and 11 insecticides) in this beverage. Parameters affecting the sensitivity, selectivity, accuracy and robustness of the method are evaluated as function of sample volume, clean-up conditions, and number of extraction-desorption cycles performed with the same SPE cartridgeengAttribution-NonCommercial-NoDerivatives 4.0 Internacional© 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)http://creativecommons.org/licenses/by-nc-nd/4.0/PesticidesWineOn-line SPELiquid chromatographyTandem mass spectrometryjournal article10.1016/j.jfca.2021.104184open access