Rúa Sueiro, MarcosMunín Cruz, PaulaReigosa Chamorro, FranciscoVila Abad, José ManuelOrtigueira Amor, Juan Manuel2021-02-152021-02-152021Proceedings 2020, 62(1), 13; https://doi.org/10.3390/proceedings2020062013http://hdl.handle.net/10347/24466Cyclometallated compounds have been extensively studied, in particular those with palladium and platinum. This is because of their possible applications in medicinal chemistry, as anticancer or antimicrobial agents; in some cases, with similar results as cisplatin, carboplatin or oxaliplatin. What is also remarkable is their use as homogeneous catalysts, for example, in cross coupling reactions such as Suzuki–Miyaura or Mizoroki–Heck. Herein, we report the synthesis of different thiosemicarbazone ligands, which will be reacted with a palladium or platinum salt, to give the corresponding cyclometallated compounds; in addition, their reactivity with bis(diphenylphosphino)methane (dppm) will be studied. Characterization has been carried out by elemental analysis, IR spectroscopy, 1H and 31P NMR spectroscopy. Additionally, 1c has been studied by X-ray diffractioneng© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/CyclometallationThiosemicarbazonePalladiumPlatinumX-ray diffractionjournal article10.3390/proceedings20200620132504-3900open access