Pérez Camiña, JesúsGarcía-Caballero Parada, TomásCid Díaz, Tania2020-07-212020-07-212020http://hdl.handle.net/10347/23179Many pathological states characterized by muscle atrophy are associated with an increase in circulating glucocorticoids and poor patient prognosis. The development of treatments for glucocorticoid-induced wasting in skeletal muscle should be designed based on how the balance of muscle protein synthesis and degradation is deregulated. Here, we investigated whether the obestatin/GPR39 system, an autocrine/paracrine signaling system acting on myogenesis and with anabolic effects on the skeletal muscle, could protect against glucocorticoid- induced muscle cell atrophy.engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Obestatin signalingSkeletal muscleSkeletal muscle atrophySkeletal muscle cell atrophyMaterias::Investigación::24 Ciencias de la vida::2411 Fisiología humana::241110 Fisiología del músculoMaterias::Investigación::32 Ciencias médicas::3205 Medicina interna::320502 Endocrinologíadoctoral thesisopen access