Rodríguez Holguín, SocorroCorral Varela, María MontserratCadaveira Mahía, Fernando2021-02-152021-02-151998Rodríguez Holguín, S., Corral, M., Cadaveira, F. (1998). Visual and auditory event-related potentials in young children of alcoholics from high- and low-density families. Alcoholism, Clinical and Experimental Research, 22(1), 87–960145-6008http://hdl.handle.net/10347/24444Event-related potentials (ERPs), particularly the P3 wave, have been proposed as biological markers of genetic risk for alcoholism. The present study assesses the ERPs from 102 boys and girls (7 to 15 years old) divided into three groups: two groups of sons and daughters of alcoholic fathers, with and without other first- or second-degree relatives affected, and a control group of children of nonalcoholics. Both visual and auditory discrimination tasks with three stimuli (standard, target, and infrequent nontarget) were used. P3 amplitudes did not reach significant reduction for the high-risk males and were complex for females. There were significant differences among females in P3 visual latency elicited by targets; delays in this variable were associated with multigenerational familial alcoholism. Results are discussed in light of the tasks used for eliciting the ERPs and the characteristics of the selected sampleengCopyright © 1998 by The Research Society on Alcoholism. This article may be used for non-commercial purposes in accordance with Wiley, Research Society on Alcoholism, and International Society for Biomedical Research on Alcoholism terms and conditions for use of self-archived versionsEvent-related potentialsChildren of alcoholicsFamily historyPotenciais evocadosFillos de alcohólicosHistoria familiarPotenciales evocadosHijos de alcohólicosjournal article10.1111/j.1530-0277.1998.tb03620.xopen access