Pazo Pascual, MartaFernández Caro, HéctorPriegue Caamaño, Juan ManuelLostalé Seijo, IreneMontenegro García, Javier2017-02-132017-02-132017-01-25Montenegro, Javier, Pazo, Marta, Fernández-Caro, Héctor, Priegue, Juan and Lostalé-Seijo, Irene, 2017, Tuning the Properties of Penetrating Peptides by Oxime Conjugation. Synlett. 2017. DOI 10.1055/s-0036-1588689. Thieme Publishing Group0936-5214http://hdl.handle.net/10347/15141We here describe the application of oxime bond formation between a peptide scaffold and different aldehydes to modify the transporting capabilities of penetrating peptides. We show that bonds such as oximes offer a great synthetic advantage for the modification of the properties of model penetrating peptides. We believe that this approach will allow the development of improved intracellular delivery vehiclesengAtribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/Peptide chemistryPenetrating peptidesSupramolecular chemistryMembrane transportSolid-phase peptide synthesisMaterias::Investigación::23 Química::2302 Bioquímicajournal article10.1055/s-0036-15886891437-2096open access