Ruano Raviña, AlbertoFernández Villar, José AlbertoLeiro Fernández, VirginiaMouronte Roibás, Cecilia2019-06-142019-06-142019http://hdl.handle.net/10347/18876Both COPD and LC share their high mortality, tobacco history, genetic background, environmental exposure and other underlying mechanisms. The aim of this project is to establish COPD prevalence, as well as its underdiagnosis in LC patients, and to analyze their clinical profile, comparing it with a control group of patients with COPD only, evaluating different phenotypes and looking for biomarkers with potential at early diagnosis of LC or even with therapeutic and prognostic implications in this subset of patients. This work contains three different studies: a systematic review, a prospectiva cohort study basad on patients with LC with/without COPD, and two case-control study with subjects with COPD with/without LC.engAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/COPDLung cancerEmphysemaBiomarkersMaterias::Investigación::32 Ciencias médicas::3205 Medicina interna::320508 Enfermedades pulmonaresMaterias::Investigación::32 Ciencias médicas::3201 Ciencias clínicas::320101 Oncologíadoctoral thesisopen access