Rama, GustavoArdá, AnaMaréchal, Jean-DidierGamba, IlariaIshida, HitoshiJiménez Barbero, JesúsVázquez Sentís, Marco EugenioVázquez López, Miguel2018-07-102018-07-102012-05-03Rama, G., Ardá, A. , Maréchal, J., Gamba, I., Ishida, H., Jiménez‐Barbero, J., Vázquez, M. E. and Vázquez López, M. (2012), Stereoselective Formation of Chiral Metallopeptides. Chem. Eur. J., 18: 7030-7035. doi:10.1002/chem.201201036http://hdl.handle.net/10347/17008This is the peer reviewed version of the following article: Rama, G., Ardá, A., Maréchal, J., Gamba, I., Ishida, H., Jiménez‐Barbero, J., Vázquez, M. E. and Vázquez López, M. (2012), Stereoselective Formation of Chiral Metallopeptides. Chem. Eur. J., 18: 7030-7035, which has been published in final form at https://doi.org/10.1002/chem.201201036. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived VersionsPlaying into our hands: The achiral bipyridine amino acid fluorenylmethyloxycarbonyl 5‐amino‐3‐oxapentanoic acid (Fmoc‐O1PenBpy‐OH) has been used for the solid‐phase synthesis of metallopeptides. Circular dichroism, molecular modeling, and NMR spectroscopic studies show that the chirality of the resulting metal complexes in aqueous solution is determined, and can thus be controlled, by the stereochemistry of one proline residue in the loop between the two coordinating O1PenBpy residueseng© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This article may be used for non-commercial purposes in accordance with Wiley-VCH Terms and Conditions for Self-ArchivingChiralityLigand effectsMetallopeptidesMolecular modelingNMR spectroscopyPeptidesjournal article10.1002/chem.2012010361521-3765open access