Jinadasa, Kolita Kamal Bedigama KankanamgePeña Vázquez, Elena MaríaBermejo Barrera, PilarMoreda Piñeiro, Antonio2024-02-082024-02-082020Jinadasa, B.K.K.K., Peña Vázquez, E., Bermejo Barrera, P., Moreda Piñeiro, A. (2020). Synthesis and application of a surface ionic imprinting polymer on silicacoated Mn-doped ZnS quantum dots as a chemosensor for the selective quantification of inorganic arsenic in fish. "Analytical and Bioanalytical Chemistry", vol. 412, Issue 7, 1663-16731618-2642http://hdl.handle.net/10347/32571This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00216-020-02405-1A novel room temperature phosphorescence chemosensor probe has been successfully developed and applied to the selective detection and quantification of inorganic arsenic (As(III) plus As(V)) in fish samples. The prepared material (IIP@ZnS:Mn QDs) was based on Mn-doped ZnS quantum dots coated with (3-aminopropyl) triethoxysilane and an As(III) ionic imprinted polymer. The novel use of vinyl imidazole as a complexing reagent when synthesizing the ionic imprinted polymer guarantees that both inorganic arsenic species (As(III) and As(V)) can interact with the recognition cavities in the ionic imprinted polymer. After characterization, several studies were performed to enhance the interaction between the targets (As(III) and As(V) ions) and the IIP@ZnS:Mn QDs nanoparticles. The optimization and validation process showed that the composite material offers high selectivity (high imprinting factor) for inorganic arsenic species. The limit of quantification for total inorganic As was 29.6 μg kg-1, value lower than the EU/EC regulation limits proposed for other foodstuffs than fish, such as rice. The proposed method is therefore simple, requires short analysis times and offers good sensitivity, precision (inter-day relative standard deviations lower than 10%), and quantitative analytical recoveries. The method has been successfully applied to assess total inorganic arsenic in several fishery products, showing good agreement with the total inorganic arsenic concentration (As(III) plus As(V)) found after applying other advanced and expensive methods such those based on high performance liquid chromatography hyphenated to inductively coupled plasma – mass spectrometryengCopyright © 2020, Springer-Verlag GmbH Germany, part of Springer Naturehttp://creativecommons.org/licenses/by-nc-nd/4.0/Silica-coated Mn-doped ZnS quantum dotsIonic imprinted polymerRoom temperature phosphorescenceInorganic arsenicFishChemosensor probe2301 Química Analíticajournal article10.1007/s00216-020-02405-11618-2650open access