Seoane Fernández, AndrésMascareñas Cid, José Luis2022-09-222022-09-222022Eur. J. Org. Chem. 2022, e2022001181434-193Xhttp://hdl.handle.net/10347/29239Transition-metal catalyzed reactions are being increasingly used in biological contexts and even in living cells and organisms. Most of the processes so far developed rely on the ability of metal complexes to bind and activate unsaturated systems in a bioorthogonal way. The reactions are often tracked by fluorescence microscopy, by using reaction probes that emit light only after the reactioneng© 2022 The Authors. European Journal of Organic Chemistry published by Wiley-VCH GmbH This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are madeAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/BiocatalysisBioorthogonalChemical biologyCell biologyOrganometallic catalysisjournal article10.1002/ejoc.2022001181099-0690open access