RT Journal Article T1 Bioaccumulation of organophosphorus flame retardants in the marine mussel Mytilus galloprovincialis A1 Mata, María del Carmen A1 Castro Bustelo, Verónica A1 Quintana Álvarez, José Benito A1 Rodil Rodríguez, María del Rosario A1 Vidal-Liñán, Leticia K1 OPFRs K1 MSPD K1 Kinetics K1 Kow AB The bioaccumulation and depuration of seven organophosphorus flame retardants (OPFRs) in marine mussel Mytilus galloprovincialis were studied. OPFRs showed to be bioavailable in aquatic environments. When mussels are exposed to environmentally relevant concentrations of OPFRs, uptake kinetics fit well to a first-order model with a single compartment; in contrast depuration rates were generally underestimated by that model, most likely because it does not take into account the biotransformation of OPFRs by the organisms. The highest bioaccumulation rates were observed for tricresyl phosphate (TCrP), triphenyl phosphate (TPhP) and 2-ethylhexyldiphenylphosphate (EHDPP). This could be due to the presence of aryl groups in these compounds, their low solubility in water, and their affinity for fat tissues. According to these findings TCrP, with a BCF value of 4042 L kg−1 wet weight, should be classified in environmental regulations as an accumulative chemical PB Elsevier SN 0048-9697 YR 2021 FD 2021 LK http://hdl.handle.net/10347/27008 UL http://hdl.handle.net/10347/27008 LA eng NO M.C. Mata et al. Science of the Total Environment, 2022, 805, 150384 NO This research was supported by the Spanish Government through research project BIOPLAS (PID2019-108857RB-C32), the Spanish Agencia Estatal de Investigación (ref. CTM2017-84763-C3-R-2), Xunta de Galicia (ED431C2017/36 and Verónica Castro predoctoral contract, ref.: ED481A-2017/156) and FEDER/ERDF funds. This work has received financial support from the Xunta de Galicia (Centro de investigación de Galicia accreditation 2019-2022) and the European Union (European Regional Development Fund - ERDF) DS Minerva RD 24 abr 2026