RT Journal Article
T1 Diabetes mellitus and oral lichen planus: A systematic review and meta-analysis
A1 Mallah, Narmeen
A1 Varela Centelles, Pablo Ignacio
A1 Seoane Romero, Javier
A1 Takkouche, Bahi
K1 Diabetes mellitus
K1 Meta-analysis
K1 Oral lichen planus
AB Objective: To undertake a meta-analysis of the association of Oral Lichen Planus (OLP) with diabetes, two diseases with an important impact on public health and the economy, but the evidence of which about their association is inconsistent.Methods: Relevant studies were localized by searching MEDLINE, EMBASE, Conference Proceedings, and other databases from inception to October 2020, without restrictions. The reference lists of included studies and of related reviews were also inspected. Global pooled odds ratios were calculated, and predefined subgroup analyses were performed. The heterogeneity between studies and publication bias was assessed and sensitivity analysis was carried out.Results: Thirty-two studies were included in the meta-analysis. Pooled ORs showed a moderate association between diabetes and OLP [OR: 1.87 (95%CI: 1.57, 2.34)]. The association is limited to studies carried out on adults only [OR: 2.12 (95%CI: 1.75, 2.57)] and is observed in all study designs. Globally, the heterogeneity was low to moderate. Studies carried out in European populations show a stronger association of diabetes and OLP than Asiatic studies [OR: 2.49 (95%CI: 1.87, 3.32) and 1.60 (95%CI: 1.25, 2.03), respectively].Conclusions: Diabetes and OLP are moderately associated. Systematic diagnosis of diabetes in OLP patients could prove useful
PB Wiley
YR 2021
FD 2021
LK http://hdl.handle.net/10347/26449
UL http://hdl.handle.net/10347/26449
LA eng
NO Mallah, N., Ignacio Varela-Centelles, P., Seoane-Romero, J., & Takkouche, B. (2021). Diabetes mellitus and oral lichen planus: A systematic review and meta-analysis. Oral Diseases, 00, 1– 10. https://doi.org/10.1111/odi.13927
DS Minerva
RD 27 abr 2026